Help Prevent Adverse Drug Events for Newborns Up to Age One

Neonatal and infant patients are considered to be at higher risk for ADEs, due to the nature of these patients, especially in hospital acute care settings. Studies have also shown that pediatric patients may be more vulnerable to the consequences of medication errors than adult patients.

Drawing on the expertise of First DataBank's experienced pediatric clinical pharmacists, the Neonatal and Infant Dosage Range Check Module offers specialized dosing information for this population—to include dosing for premature neonates—while complementing our adult dosing modules. This dose range content accommodates the narrow therapeutic window for neonates and infants, preventing dosing errors in these patients by factoring in several critical characteristics, including weight, gestational age at birth and medical condition, when available. Medication screening covers those drugs most commonly prescribed for newborns in an acute-care setting.

Checks and Recommendations

The Neonatal and Infant Dosage Range Check Module offers healthcare providers the following recommendations:

• Apparent half-life
• Age ranges from 0 to 65+
• Creatinine clearance thresholds
• Dosing requency or frequency range
• Duration of therapy (minimum and maximum lengths)
• Dose types, such as loading, initial, maintenance, etc.
• Renal and hepatic impairment dosage adjustment indicators
• Maximum single dose
• Maximum lifetime dose

When a medication dose for a newborn falls outside an acceptable dose range, frequency of administration or duration range for a given drug, this screening module enables a pharmacy or clinical information system to display a brief warning message alerting the healthcare provider to re-evaluate the appropriateness of the proposed dose.

Use With Other First DataBank Products

First DataBank's dosing modules can also be embedded into virtually any healthcare information system, using our content-integration software, the Drug Information Framework. This not only enables developers to build healthcare solutions faster and more economically, it also simplifies the process of customizing clinical modules so that clinician user organizations can set their own dosage ranges, interaction severity levels and drug pick lists.